No. There is no absolutely sure way to protect your assets from creditors. However, with the right planning, you can make it so hard for creditors to collect from your assets that they will not want to incur the expense and time involved in pursuing their claim against you.
Despite this, many people think they are protected by simply placing valuable assets in the name of their spouse. Without expert help and the right agreements, simply transferring title of a valuable asset to your spouse does not work.